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dc.contributor.authorSanta, Cristiam Fernando-
dc.contributor.authorLópez Osorio, Betty Lucy-
dc.date.accessioned2024-03-05T23:23:22Z-
dc.date.available2024-03-05T23:23:22Z-
dc.date.issued2013-03-01-
dc.identifier.issn0370-3908spa
dc.identifier.urihttps://repositorio.accefyn.org.co/handle/001/2828-
dc.description.abstractLa aparición de nuevas enfermedades, así como la falta de un procedimiento eficaz y menos tóxico para el tratamiento enfermedades como el cáncer, han impulsado el desarrollo de sistemas de transporte y liberación controlada de fármacos. La nanomedicina, un área de gran crecimiento durante las últimas decadas, hace uso de ensambles nanométricos (nanotransportadores) para la liberación controlada de medicamentos. Esta, no solo supera los inconvenientes de los tratamientos clásicos de las enfermedades, si no que también aporta diversas mejoras y nuevas posibilidades. El presente trabajo presenta una revisión de los principales aspectos del diseño de nanotransportadores poliméricos para la liberación controlada de medicamentos.spa
dc.description.abstractThe appearance of new diseases and the lack of effective treatments of diseases like cancer have enhanced the development of controlled drug transport and delivery systems. Nanomedicine, one area that has grown through the last decades, uses nanometric assemblies (nanotransporters), for controlled drug delivery. Nanomedicine not only overcomes the drawbacks of classical treatments of diseases, but presents benefits and new possibilities. This papers review the main aspects for the design of the polymeric nanotransporters for controlled drug delivery.eng
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dc.publisherAcademia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.rightsLa revista de la Academia se distribuye con el modelo de acceso abierto y la licencia Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International con el fin de contribuir a la visibilidad, el acceso y la difusión de la producción científica.spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.titleMATERIALES POLIMÉRICOS EN NANOMEDICINA: TRANSPORTE Y LIBERACIÓN CONTROLADA DE FÁRMACOS.spa
dc.titlePOLYMERS IN NANOMEDICINE: CONTROLLED DRUG TRANSPORT AND DELIVERYeng
dc.typeArtículo de revistaspa
dcterms.audienceEstudiantes, maestros y comunidad científica.spa
dcterms.referencesAhmed, F. & Discher, D.E., 2004. Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-trigge red controlled release vesicles. Journal of controlled release, 96(1), :37–53.spa
dcterms.referencesAlbertazzi, L.et al., 2012. Enhanced bioactivity of internally functionalized cationic dendrimers with PEG cores. Biomacromolecules, 13(12):4089–4097.spa
dcterms.referencesBasile, L.Pignatello, R.& Passirani, C., 2012. Active targeting strategies for anticancer drug nanocarriers. Current drug delivery, 9(3):255–268.spa
dcterms.referencesBlanazs, A.Armes, S.P.& Ryan, A.J., 2009. Self-Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications. Macromolecular rapid communications, 30(4-5), :267–277.spa
dcterms.referencesBodnar, M.Hartmann, J.F.& Borbely, J., 2006. Synthesis and study of cross-linked chitosan-N-poly(ethylene glycol) nanoparticles. Biomacromolecules, 7(11), :3030–3036.spa
dcterms.referencesCabane, E.et al., 2012. Stimuli-responsive polymers and their applications in nanomedicine. Biointerphases, 7(1-4):9.spa
dcterms.referencesCaldorera-Moore, M. & Peppas, N. a, 2009. Micro- and nanotechnologies for intelligent and responsive biomaterial-based medical systems. Advanced drug delivery reviews, 61(15), :1391–1401.spa
dcterms.referencesCao, W. & Zhu, L., 2011. Synthesis and Unimolecular Micelles of Amphiphilic Dendrimer-like Star Polymer with Various Functional Surface Groups. Macromolecules, 44(6), :1500–1512.spa
dcterms.referencesChaterji, S.Kwon, I.K.& Park, K., 2007. Smart Polymeric Gels: Redefining the Limits of Biomedical Devices. Progress in polymer science, 32(8-9), :1083–1122.spa
dcterms.referencesChaudhari, K.R.et al., 2012. Opsonization, biodistribution, cellular uptake and apoptosis study of PEGylated PBCA nanoparticle as potential drug delivery carrier. Pharmaceutical research, 29(1):53–68.spa
dcterms.referencesCho, K.et al., 2008. Therapeutic nanoparticles for drug delivery in cancer. Clinical cancer research, 14(5), :1310–1316.spa
dcterms.referencesCostantino, L.et al., 2005. Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier. Journal of controlled release, 108(1), :84–96.spa
dcterms.referencesDash, T.K. & Konkimalla, V.B., 2012. Polymeric modification and its implication in drug delivery: poly-ε-caprolactone (PCL) as a model polymer. Molecular pharmaceutics, 9(9), :2365–2379.spa
dcterms.referencesDu, J. & O’Reilly, R.K., 2009. Advances and challenges in smart and functional polymer vesicles. Soft Matter, 5(19), :3544–3561.spa
dcterms.referencesEssa, S.Rabanel, J.M.& Hildgen, P., 2010. Effect of polyethylene glycol (PEG) chain organization on the physicochemical properties of poly(D, L-lactide) (PLA) based nanoparticles. European journal of pharmaceutics and biopharmaceutics, 75(2), :96–106.spa
dcterms.referencesFan, L.et al., 2008. Novel super pH-sensitive nanoparticles responsive to tumor extracellular pH. Carbohydrate Polymers, 73(3), :390–400.spa
dcterms.referencesFarokhzad, O. & Langer, R., 2009. Impact of nanotechnology on drug delivery. Acs Nano, 3(1):16–20.spa
dcterms.referencesFu, Y. & Kao, W., 2010. Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems. Expert opinion on drug delivery, 7(4), :429–444.spa
dcterms.referencesGil, E. & Hudson, S., 2004. Stimuli-reponsive polymers and their bioconjugates. Progress in Polymer Science, 29(12):1173–1222.spa
dcterms.referencesGreish, K., 2012. Enhanced permeability and retention effect for selective targeting of anticancer nanomedicine: are we there yet? Drug Discovery Today: Technologies, 9(2):e161–e166.spa
dcterms.referencesGreish, K., 2007. Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. Journal of drug targeting, 15(7-8), :457–464.spa
dcterms.referencesGrund, S.Bauer, M.& Fischer, D., 2011. Polymers in Drug Delivery-State of the Art and Future Trends. Advanced Engineering Materials, 13(3), :B61–B87.spa
dcterms.referencesHarris, J. & Veronese, F., 2003. Peptide and protein pegylation II-clinical evaluation. Advanced Drug Delivery Reviews, 55, :1259–1260.spa
dcterms.referencesHomberg, K.et al., 2002. Surfactants and polymers in aqueous solution 2nd ed., John Wiley & Sons, Ltd.spa
dcterms.referencesHu, J.et al., 2012. A review of stimuli-responsive polymers for smart textile applications. Smart Materials and Structures, 21(5), :053001.spa
dcterms.referencesHuang, M.Khor, E.& Lim, L.-Y., 2004. Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharmaceutical research, 21(2), :344–353.spa
dcterms.referencesKnop, K.et al., 2010. Poly(ethylene glycol) in drug delivery: pros and cons as well as potential alternatives. Angewandte Chemie (International ed. in English), 49(36), :6288–6308.spa
dcterms.referencesDe la Rica, R.Aili, D.& Stevens, M.M., 2012. Enzyme-responsive nanoparticles for drug release and diagnostics. Advanced drug delivery reviews, 64(11), :967–978.spa
dcterms.referencesLi, F.et al., 2009. Study of dual responsive poly[(maleilated dextran)- graft -( N -isopropylacrylamide)] hydrogel nanoparticles: preparation, characterization and biological evaluation. Polymer International, 58(9), :1023–1033.spa
dcterms.referencesMahmoudi, M.et al., 2011. Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy. Advanced drug delivery reviews, 63(1-2):24–46.spa
dcterms.referencesMartín del Valle, E.M.Galán, M.A.& Carbonell, R.G., 2009. Drug Delivery Technologies: The Way Forward in the New Decade. Industrial & Engineering Chemistry Research, 48(5), :2475–2486.spa
dcterms.referencesMeng, F.Zhong, Z.& Feijen, J., 2009. Stimuli-responsive polymersomes for programmed drug delivery. Biomacromolecules, 10(2), :197–209.spa
dcterms.referencesNobs, L.et al., 2004. Poly(lactic acid) nanoparticles labeled with biologically active Neutravidin for active targeting. European journal of pharmaceutics and biopharmaceutics, 58(3), :483–490.spa
dcterms.referencesOgier, J.Arnauld, T.& Doris, E., 2009. Recent advances in the field of nanometric drug carriers. Future Medicinal Chemistry, 1(4), :693–711.spa
dcterms.referencesPapadimitriou, S. aAchilias, D.S.& Bikiaris, D.N., 2012. Chitosan-g-PEG nanoparticles ionically crosslinked with poly(glutamic acid) and tripolyphosphate as protein delivery systems. International journal of pharmaceutics, 430(1-2):318–327.spa
dcterms.referencesPark, J.H.et al., 2010. Targeted delivery of low molecular drugs using chitosan and its derivatives. Advanced drug delivery reviews, 62(1):28–41.spa
dcterms.referencesQi, L. & Gao, X., 2008. Emerging application of quantum dots for drug delivery and therapy. Expert opinion on drug delivery, 5(3), :263–267.spa
dcterms.referencesQiu, L.Y. & Bae, Y.H., 2006. Polymer architecture and drug delivery. Pharmaceutical research, 23(1):1–30.spa
dcterms.referencesRancan, F.et al., 2009. Investigation of polylactic acid (PLA) nanoparticles as drug delivery systems for local dermatotherapy.spa
dcterms.referencesPharmaceutical research, 26(8), :2027–2036.spa
dcterms.referencesRodríguez-García, R.et al. , 2011. Polymersomes: smart vesicles of tunable rigidity and permeability. Soft Matter, 7(4), :1532–1542.spa
dcterms.referencesStolnik, S.Illum, L.& Davis, S.S., 1995. Long circulating microparticulate drug carriers. Advanced Drug Delivery Reviews, 16(2-3), :195–214.spa
dcterms.referencesVilar, G.Tulla-Puche, J.& Albericio, F., 2012. Polymers and drug delivery systems. Current drug delivery, 9(4):367–394.spa
dcterms.referencesWang, S.Liu, M.& Kang, K., 2013. Magnetic Nanoparticles and Thermally Responsive Polymer for Targeted Hyperthermia and Sustained Anti-Cancer Drug Delivery. In W. J.spa
dcterms.referencesWelchet al., eds. Oxygen Transport to Tissue XXXIV SE 44. Springer New York, :315–321 LA – English.spa
dcterms.referencesXiao, R.Z.et al., 2010. Recent advances in PEG-PLA block copolymer nanoparticles. International journal of nanomedicine, 5, :1057–1065.spa
dcterms.referencesYu, S.S.et al., 2013. Macrophage-Specific RNAi Targeting via “Click”, Mannosylated Polymeric Micelles. Molecular Pharmaceutics:130120103716005spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.versioninfo:eu-repo/semantics/updatedVersionspa
dc.rights.creativecommonsAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)spa
dc.identifier.doihttps://doi.org/10.18257/raccefyn.37(142).2013.2538-
dc.subject.proposalNanomedicinaspa
dc.subject.proposalNanomedicineeng
dc.subject.proposalTransporte y liberación controlado de fármacosspa
dc.subject.proposalControlled drug transport and deliveryeng
dc.subject.proposalNanotranportadores poliméricosspa
dc.subject.proposalPolymeric nanotransporterseng
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.relation.ispartofjournalRevista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.relation.citationvolume37spa
dc.relation.citationstartpage79spa
dc.relation.citationendpage88spa
dc.contributor.corporatenameAcademia Colombiana de Ciencias Exactas, Físicas y Naturalesspa
dc.identifier.eissn2382-4980spa
dc.relation.citationissue142spa
dc.type.contentTextspa
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